Absorptive capacity facilitates adaptation to novel environmental disasters

Absorptive capacity–the ability to learn and apply external knowledge and information to acquire material resources–is an essential but overlooked driver in community adaptation to new and unprecedented disasters. We analyzed data from a representative random sample of 603 individuals from 25 coastal communities in Louisiana affected by the Deepwater Horizon oil spill. We used simultaneous equation models to assess the relationship between absorptive capacity and resource acquisition for affected individuals after the disaster. Results show that the diversity of individuals’ prior knowledge coupled with the community’s external orientation and internal cohesion facilitate resource use. They go beyond simply providing resources and demonstrate individual and community features necessary for absorbing information and knowledge and help devise adaptation strategies to address the dynamics of changing economic, social, and political environment after the disaster

Sensing Physiological Change and Mental Stress in Older Adults From Hot Weather

This study combines wearable sensors, weather data, and self-reported mood surveys to assess mental stress on older adults from heat experience. It is designed as a pilot and feasibility study in preparation for a large-scale experiment of older adults' mental wellbeing during extreme heat events. Results show that on-body temperatures from two i-Button sensors coupled with heart rate monitored from a smart watch are important indicators to evaluate individualized heat stress given a relatively uniform outdoor temperature. Furthermore, assessing their mood in their own environment demonstrates potential for understanding mental wellbeing that can change with varying time and location

Climate Decision-Making

Climate change decision-making has emerged in recent decades as an area of research and practice, expanding on an earlier focus on climate policy. Defined as the study of decisions relevant for climate change, it draws on developments in decision science, particularly advances in the study of cognitive and deliberative processes in individuals and organizations. The effects of climate, economic, social, and other framings on decision-making have been studied, often showing that nonclimate frames can be as effective as, or more effective than, climate frames in promoting decision-making and action. The concept of urgency, linked to the ideas of climate crisis and climate emergency, has taken on importance in recent years. Research on climate decision-making has influenced numerous areas of climate action, including nudges and other behavioral interventions, corporate social responsibility, and Indigenous decision-making. Areas of transformational change, such as strategic retreat in the face of sea-level rise, are emerging

Mixed methods in land change research: towards integration

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89580/1/j.1475-5661.2011.00482.x.pd

Advances in Non-Invasive Blood Pressure Monitoring

This paper reviews recent advances in non-invasive blood pressure monitoring and highlights the added value of a novel algorithm-based blood pressure sensor which uses machine-learning techniques to extract blood pressure values from the shape of the pulse waveform. We report results from preliminary studies on a range of patient populations and discuss the accuracy and limitations of this capacitive-based technology and its potential application in hospitals and communities

Risk Management and Adaptation for Extremes and Abrupt Changes in Climate and Oceans: Current Knowledge Gaps

Perspectives for risk management and adaptation have received ample attention in the recent IPCC Special Report on Changes in the Oceans and Cryosphere (SROCC). However, several knowledge gaps on the impacts of abrupt changes, cascading effects and compound extreme climatic events have been identified, and need further research. We focus on specific climate change risks identified in the SROCC report, namely: changes in tropical and extratropical cyclones; marine heatwaves; extreme ENSO events; and abrupt changes in the Atlantic Meridional Overturning Circulation. Several of the socioeconomic impacts from these events are not yet well-understood, and the literature is also sparse on specific recommendations for integrated risk management and adaptation options to reduce such risks. Also, past research has mostly focussed on concepts that have seen little application to real-world cases. We discuss relevant research needs and priorities for improved social-ecological impact assessment related to these major physical changes in the climate and oceans. For example, harmonised approaches are needed to better understand impacts from compound events, and cascading impacts across systems. Such information is essential to inform options for adaptation, governance and decision-making. Finally, we highlight research needs for developing transformative adaptation options and their governance

The Skin Antiseptic agents at Vaginal dElivery (SAVE) trial: study protocol for a randomized controlled trial

Background Cleansing of the vulva and perineum is recommended during preparation for vaginal delivery, and special attention is paid to cleansing before episiotomy because episiotomy is known to increase the risk of perineal wound infection and/or dehiscence. However, the optimal method of perineal cleansing has not been established, including the choice of antiseptic agent. To address this issue, we designed a randomized controlled trial to examine whether skin preparation with chlorhexidine-alcohol is superior to povidone-iodine for the prevention of perineal wound infection after vaginal delivery. Methods In this multicenter randomized controlled trial, term pregnant women who plan to deliver vaginally after episiotomy will be enrolled. The participants will be randomly assigned to use antiseptic agents for perineal cleansing (povidone-iodine or chlorhexidine-alcohol). The primary outcome is superficial or deep perineal wound infection within 30 days after vaginal delivery. The secondary outcomes are the length of hospital stay, physician office visits, or hospital readmission for infection-related complications, endometritis, skin irritations, and allergic reactions. Discussion This study will be the first randomized controlled trial aiming to determine the optimal antiseptic agent for the prevention of perineal wound infections after vaginal delivery. Trial registration ClinicalTrials.gov NCT05122169. First submitted date on 8 November 2021. First posted date on 16 November 202

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis; however, treatment options remain limited. Here we report the construction of 264 signature-tagged gene-deletion strains for 129 putative kinases, and examine their phenotypic traits under 30 distinct in vitro growth conditions and in two different hosts (insect larvae and mice). Clustering analysis of in vitro phenotypic traits indicates that several of these kinases have roles in known signalling pathways, and identifies hitherto uncharacterized signalling cascades. Virulence assays in the insect and mouse models provide evidence of pathogenicity-related roles for 63 kinases involved in the following biological categories: growth and cell cycle, nutrient metabolism, stress response and adaptation, cell signalling, cell polarity and morphology, vacuole trafficking, transfer RNA (tRNA) modification and other functions. Our study provides insights into the pathobiological signalling circuitry of C. neoformans and identifies potential anticryptococcal or antifungal drug targets.OAIID:RECH_ACHV_DSTSH_NO:T201615370RECH_ACHV_FG:RR00200001ADJUST_YN:EMP_ID:A003535CITE_RATE:11.329FILENAME:4. ncomms12766.pdfDEPT_NM:농생명공학부EMAIL:[email protected]_YN:YFILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/fce63c4a-7de7-4741-996f-d8d24af38905/linkCONFIRM: